Wednesday, September 16, 2015

Could someone tell me about the human reproductive hormone which is the base of contraceptive drugs?

Contraceptives are some Hormonal preparations that make a concentration, cycling, of female specific sex hormones,  similar to that normally made by the endocrine function of the ovary (mainly, in the absence of administration of  Contraceptives, the ovary is largely responsible with female sex hormone secretion, also it's task being the process of ovulation = removal of female sex cell, capable of being fertilized by sperm).


The contribution of exogenous (outside) sex hormones, hormone secretion function of the ovary is no longer found as being useful, resulting  the rest of the ovary, which involves inhibiting ovulation and thus  the contraception being realized (oocyte is not eliminated , not fecundation occurs so there is no question of pregnancy).


About 10 years ago it was discovered that the birds produce a hormone which has results in suppression of reproduction.


This hormone, known as gonadotropin inhibitory hormone (GnIH), has the effect of blocking the hormones that prepare the body for procreation.But this hormone has not only  the blocking effect of reproductive hormones, but it can also function as blocking the growth of cancer cells. The current recommended therapy for treating types of cancer that reproductive hormones are responsible, are increased amounts of gonadotropin releasing hormones, this fact creating side-effects.


The effect of reproductive's inhibition which this hormone shows it, it is done at different levels on the reproductive axis (receptors found in hypothalamus and pituitary) :


-GnIH can inhibit the release of GnRH from the hypothalamus;


-GnIH could have an influence on the gonads;


-GnIH could have an influence on pituitary's receptors.

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