What are five bad things about the Colony of Virginia?

It certainly wasn't the best place they could have chosen to land, and the fact they had been on the ocean for weeks no doubt influenced their decision.

Much of the colony was a swamp, which bred huge swarms of mosquitoes and invited malaria.  It was also difficult to farm those regions without first draining them.

The land was undeveloped, and had to be hacked out of the wilderness.

Relations with the Native tribes were often testy at best, and it made it difficult to increase settlement on the frontier.

It was difficult to get labor to the colony.  Indentures were expensive and temporary, and slaves had to be imported from long distances.

It was difficult to convince women to settle there, and this made male settlers restless, in part causing Bacon's Rebellion.