Thursday, March 15, 2012

What are the indications for use of Q10 ?

Coenzyme Q10 (CoQ10, Ubiquinone ) is a substance with a similar role as vitamins present in all body cells, especially those with very intense activity: heart, liver, brain.


Is involved in all processes of energy production and energy storage in cells also has important antioxidant role by inactivating free radicals responsible for cellular destruction.


Q10 was introduced to treat heart failure in Japan since 1974 and is present on the market as a dietary supplement.


Q10 has shown therapeutic properties in cardiovascular diseases, especially heart failure, and cancer, multiple sclerosis and periodontal disease, but also for strengthening the immune system and energy recovery and fast recovery after exercise.


It can be administered in combination with other drugs (eg beta blockers) to counter the undesirable effects on heart function, muscle or other organs.


Cardiovascular diseases


Researches about the action of Q10 in cardiovascular disease dates back to the late 80's. However, there is controversy among experts on effectiveness of Q10 in the treatment of heart failure. There is no evidence on the role of Q10 in the treatment of hypertension or angina.


Cancer


Since 1964, it was observed that the blood of patients with cancer (myeloma, lymphoma, breast cancer, lung, prostate, pancreas, colon, kidney) shows lower levels of Q10. Some researchers have suggested that the boost action of the immune system, would be useful in treating cancer. Q10 provides protection against cardiotoxic action of doxorubicin.


Three trials, conducted on 41 women with breast cancer who received Q10 along with conventional treatment, showed an improvement of therapy results. However, it is considered weak the correlation between the use and effectiveness of Q10 in cancer therapy.


Other conditions


Studies have shown no efficiency of Q10 in:


- Periodontal diseases


- Muscular dystrophy


- Recovery of the body after  effort.

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